Water for Pharmaceutical Industry
The water used in the pharmaceutical industry, used both in drug synthesis, cleaning, as well as Water for Injection needs to meet strict quality requirements. Water Treatment Systems and process equipment for the pharmaceutical industry need to be sanitizeable by steam and for this reason materials are used that can withstand high temperatures.
The eight types of water used in the pharmaceutical industry are:
2. Potable (drinkable) water
3. USP purified water
4. USP water for injection (WFI)
5. USP sterile water for injection
6. USP sterile water for inhalation
7. USP bacteriostatic water for injection
8. USP sterile water for irrigation
Waste water generated by the pharmaceutical industry also needs to be treated to meet strict discharge limits. High COD waters and active pharmaceutical ingredients need to me removed. In fact there is published data and investigations that assert that pharmaceuticals are making it into the environment either through waste water discharge from pharmaceutical plants, through human sanitary waste and through lanfill waste leachate. Read this article for more info. Biological treatment is one method that is used, but if the COD is very high, incineration or Wet Air Oxidation might be needed.
Another important concept in the pharmaceutical industry is GMP and Validation.
Validation can be defined as process of establishing through documented evidence a high degree of assurance that a specific process will consistently produce a product that meets its predetermined specifications and quality attributes. A validated manufacturing process is one that has been proven to do what it purports or is represented to do. The proof of validation is obtained through collection and evaluation of data, preferably beginning from the process development phase and continuing through the production phase. Validation necessarily includes process qualification (the qualification of materials, equipment, systems, buildings, and personnel), but it also includes th
Key players in the pharmaceutical water treatment industry are:
Compiled by Rami E. Kremesti